COMPOSITION:
(Lidocaine hydrochloride + Gabapentin + methylparaben + Propylparaben)
Lidocaine hydrochloride IP 5.00% w/w
- Local anaesthetic, prevents pain by blocking the signals at the nerve endings.
- Blocks Na+ & K+ ion channels and regulates intracellular & extracellular calcium concentration through other ligand-gated ion channels and Voltage-Gated Na+ channels.
Gabapentin Ip 6.00% w/w
- An anti-epileptic drug works by binding to the specific site on Voltage-Gated-Calcium-Channels that help in reducing nerve pain.
- Decreases in the density of Calcium channels in the pre-synaptic terminals leads decreased release of neurotransmitters such as Glutamate, Substance-P, CGRP (+) that are involved in neuropathic pain progression.
Preservatives
- Methylparaben IP 0.10% w/w
- Propylparaben IP 0.05% w/w